Research Tissue Bank
The PREDICT-Meso RTB will collect, store and share samples and data for PREDICT-Meso Network related activities including:
research-specific samples and data collected prospectively for PREDICT-Meso studies, which will have their own study-specific REC covering all activities in that study
surplus tissues at designated sites, as per current practice by NHSGCC biorepository and MesobanK
unconsented surplus tissue from pathology service diagnostic tissue archives in line with MRC and HTA guidelines on use of existing holdings
What types of research may be undertaken?
The Access Process
Requests for access to tissue and data will be assessed on the following criteria:
Availability of samples and data
Proposed project’s adherence with formal ethical and other approvals and patients’ authorisation for use of data and samples
Scientific value and public interest
Appropriate research infrastructure in place to make best use and tissue/data availability
Sample Access Costs
Policy for feedback of research specific findings
Researchers who receive samples or data will be required to provide the PREDICT-Meso RTB with a fully documented electronic copy of the final dataset and analytical programs. The return of research data will ensure there is no repetition of analyses and may contribute to a central repository of research data, therefore cumulatively adding value to the tissue bank. These results will be communicated to the whole of the Network and could be used to inform the design of further experiments performed within Network. In this way, external analyses, by researchers with additional expertise, will maximise the yield of data gathered from the stored tissue samples to better inform the overall understanding of mesothelioma.
Other Policies and Considerations
Use of samples and data will be restricted to projects that are aimed to improve the understanding of the pathogenesis and treatment of mesothelioma and related diseases.
Conditions of access will include acknowledgment of PREDICT-Meso in publications to allow for tracking of scientific accomplishments made possible by the availability of specimens and data .
Results generated using PREDICT-Meso RTB samples will be collated via the PREDICT-Meso Network and distributed in a number of ways including:
discussion within the Network and associated research groups
presentation at local, national and international scientific meetings
publication within peer reviewed clinical and scientific journals
publication on the PREDICT-Meso Website
preparation of preliminary (pilot) data to support future funding applications
PREDICT-Meso Research Tissue Bank (PREDICT-Meso RTB) Application form
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